An Egyptair flight with 66 people on board crashed while en route from Paris to Cairo on Thursday, the French president confirmed.
Flight MS804 left Charles de Gaulle Airport at 11:09 p.m. Paris time (5:09 p.m. ET) and vanished over the Mediterranean Sea.
French President Francois Hollande told a press conference that the plane had crashed, but said it was too soon to speculate as to the cause.
The jet was about 10 miles into Egyptian airspace at an altitude of nearly 37,000 feet when it vanished shortly before it was due to land, according to Egyptian officials.
There were 56 passengers — including three children — along with seven crew and three “security” personnel on board the Airbus A320, Egyptair said. The airline initially had said a total of 69 people were on board but later revised the figure.
There was no official confirmation of what happened to the jet but The Associated Press quoted unnamed Egyptian authorities as saying the plane had crashed.
However, France’s Foreign Minister Jean-Marc Ayrault later told reporters “nothing is confirmed” about what happened to the airliner.
Airbus — the maker of the plane — said in a statement that it regretted to confirm that “an A320 operated by Egyptair was lost” over the Mediterranean Sea.
The company would not confirm whether the plane crashed, telling NBC News their statement referred to the jet’s disappearance from radar.
Radar showed no adverse weather in the area at the time of the jet’s disappearance.
Egyptian and Greek authorities were focusing search efforts in and over the Mediterranean Sea.
The Greek military confirmed that one of its frigates and two of its aircraft were assisting in the search, with the operation focused 130 nautical miles south-southeast of the island of Karpathos.
Two helicopters also were on standby on Karpathos, Greek Cmdr. Vasilios Beletsiotis told NBC News.
Egyptair said the flight was carrying 30 Egyptian nationals along with citizens from 11 other countries — including Canada, France, the U.K., Belgium and Iraq.
Britain’s Foreign Office told NBC News it was “in urgent contact with local authorities in Paris and Cairo” and the French Ministry of Foreign Affairs opened a crisis hotline.
French President Francois Hollande said he was in touch with his Egyptian counterpart and the two agreed to work closely to establish the circumstances of the incident “as quickly as possible.”
“I share the anguish of the families affected by this tragedy,” he said in a statement posted on his official Facebook page.
Greek air traffic controllers had a normal interaction with the Egyptair pilot as he flew above the island of Kea, according to the head of the country’s civil aviation authority.
Kostas Lyntzerikos told NBC News the plane exited Greek airspace at 3:26 a.m. local time (8:26 p.m. ET) and disappeared from radar screens two minutes later — at which point controllers notified Egyptian authorities.
France’s aviation authority, the BEA, said it was in contact with Egyptian authorities and participating in the investigation into what happened.
Airbus said the plane in question was made in 2003 and delivered to Egyptair in 2008, adding that the aircraft had accumulated around 48,000 flight hours.
“At this time no further factual information is available,” the company said in a statement. “Our concerns go to all those affected.”
According to Egyptair, the pilot of the missing plane had 6,275 flying hours, while the co-pilot had 2,766.
Ayrault, the French foreign minister, met with families of the Egyptair passengers who had gathered at the Paris airport.
He told reporters there that it was clearly an emotional time and urged a halt to speculation on what happened to the plane out of respect for the families. Supporting the families was the first “priority,” he said.
Around 15 family members of passengers on board the missing flight were at Cairo airport, according to The Associated Press. It reported that airport authorities brought doctors to the scene after several distressed relatives collapsed.
The Egyptian Information Ministry said a team had been formed to assist the families of those on board.
While there was no immediate indication of whether terrorism was involved, Egyptian aviation security has been under scrutiny since a passenger jet crashed after taking off from the country’s Sharm el-Sheikh airport in October.
ISIS claimed responsibility for downing the Metrojet plane and the tragedy raised questions about how any potential explosives may have made it on board and whether there were security failings on Egypt’s end.
Analysts were cautious about speculating on the cause of the flight’s disappearance but said terrorism cannot be ruled out.
“The current indications are leaning toward some sort of abrupt incident as opposed to some sort of gradual malfunction,” said Daniel Nisman, a security analyst at the Levantine Group.
Nisman pointed to the altitude of the plane — which he said suggested there had not been an attempt to descend due to, say, a loss of cabin pressure or engine failure.
“It doesn’t exhibit the normal features of something accidental,” he said. “Nothing should be ruled out — but that also means that malicious intent shouldn’t be ruled out either.”
“If — and totally if — it was malicious intent then it could be that it was done in order to send some sort of a message,” Nisman added, noting that Egypt has been a focus in ISIS propaganda.
Pointing to the Metrojet crash, Nisman noted that “you also have precedent, unfortunately” for Egypt being a target.
Still, he said that if a security lapse was to blame then it’s “not necessarily” Egypt’s fault — “it could mean a security lapse in Europe — which is not good,” Nisman said.