Among them is "The Mysteries of Laura" with Debra Messing starring as a homicide detective struggling to raise energetic twin sons.
Katherine Heigl tackles another starring role in "State of Affairs".
She plays a CIA analyst advising the president.
"Getting the opportunity to play this woman who's very complicated, smart, ambitious and flawed
woman is really thrilling for me," Heigl says.
Flawed also applies to Rebecca Wright, the outrageous character Kate Walsh plays in the new comedy "Bad Judge".
"I kind of describe her as a 40-something in the courtroom and about 20-something outside," Walsh says.
NBC also has two new romantic comedies.
"Marry Me" stars Casey Wilson and Ken Marino as a couple of the verge of getting engaged, while "A to Z" charts the early stages of a relationship with Ben Feldman and former "how I Met Your Mother" star Cristin Milioti.
Finally, different scares are on tap with the supernatural drama "Constantine".
The DC Comics hero joins "Grimm" on Friday nights.
The network also announced that "The Blacklist" will move to Thursday nights next February for the second half of its season, just days after the series gets a special airing right after the Super Bowl.
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